Whoopi Goldberg CBD Gummies Mechanical, Injuries, Acquired problems or illnesses, Infections or tumors. Mechanical reasons: These are problems with how the spine works. For instance, Spondylolistesis(deterioration of the disc one vertebrae to slide ahead over some other, causing the vertebrae to rub collectively, consequently inflicting pain). Other mechanical issues are fractures, herniated discs, spinal stenosis, spinal degeneration and sciatica.